Follow one of America’s most iconic highways on an unforgettable road trip through Missouri and Oklahoma, discovering the places, people and stories that have shaped the legendary Route 66.
Beginning in St. Louis, the gateway to the Mother Road, experience the city’s famous landmarks and Route 66 connections before heading west through Missouri’s charming communities and scenic Ozark landscapes. Discover historic towns, colourful murals, classic roadside attractions and the welcoming small-town character that has kept the spirit of Route 66 alive for generations.
Continue into Oklahoma, where the journey reveals another side of the Mother Road. Explore vibrant cities, nostalgic roadside landmarks and communities shaped by Western traditions, Native American heritage and the pioneering spirit of the American West. From Tulsa’s music and creative culture to Oklahoma City’s blend of history, heritage and modern experiences, each stop offers a new perspective on the stories that define this remarkable state.
Along the way, uncover Route 66 icons, discover local flavours and meet the communities that continue to celebrate the highway’s enduring legacy. From the Gateway Arch and Missouri’s Ozarks to Oklahoma’s open roads, cultural heritage and Western landscapes, this journey captures the heart and soul of America’s most famous highway.
Extend your adventure with additional time in Dallas Fort Worth or Grapevine, Texas, where you can experience authentic cowboy heritage, world-class attractions and the welcoming spirit of North Texas.
Posted by: Discover North America
Posted on: 12/09/2026